TY - CHAP M1 - Book, Section TI - Human Papillomavirus A1 - Gargano, Julia W. A1 - Markowitz, Lauri E. A2 - Boulton, Matthew L. A2 - Wallace, Robert B. Y1 - 2022 N1 - T2 - Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e AB - Advances in virology during the 1970s established the existence of multiple distinct types of human papillomavirus (HPV). These virologic discoveries, when combined with epidemiologic studies, and the recognition that viral DNA can be integrated into the host genome, enabled the eventual identification of the causal role of specific HPV types in cervical cancers and later other cancers, as well as anogenital warts and recurrent respiratory papillomatosis (RRP).1,2 These advances and the identification of HPV types 16 and 18 in the majority of cervical cancers, as well as in precancers, later led to the development of prophylactic HPV vaccines; this work was recognized with a portion of the 2008 Nobel Prize in Physiology or Medicine for Harald zur Hausen.1,3 SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1182675952 ER -