TY - CHAP M1 - Book, Section TI - Rubella A1 - Knapp, Jennifer K. A1 - Reef, Susan E. A2 - Boulton, Matthew L. A2 - Wallace, Robert B. Y1 - 2022 N1 - T2 - Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e AB - In 1941, an epidemic of congenital cataracts in Australia was observed in the wake of a large outbreak of rubella.1 Until then, Rubella was considered a mild and self-limited illness. However, it assumed new importance when the association with congenital cataracts demonstrated its ability to induce congenital malformations in infants born to susceptible women who acquired rubella during pregnancy. In the following years, a broad spectrum of congenital malformations associated with congenital infection and Congenital Rubella Syndrome (CRS) were described.2-4 The subsequent success in developing and licensing an effective vaccine to prevent rubella in 1969 remains a major public health achievement. Until recently, however, the use of rubella-containing vaccine has occurred mainly in developed countries. According to the World Health Organization (WHO) only 99 (51%) countries/territories were using rubella vaccine in their national immunization programs in 2000,5 but by February 2019, 168 (87%) countries reported using rubella-containing vaccine in their national programs.6 SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/24 UR - accessmedicine.mhmedical.com/content.aspx?aid=1182675651 ER -