TY  - CHAP
M1  - Book, Section
TI  - Key Clinical Trials & Publications in General Medicine
A1  - Huppert, Laura A.
A1  - Dyster, Timothy G.
Y1  - 2021
N1  - 
T2  - Huppert’s Notes: Pathophysiology and Clinical Pearls for Internal Medicine
AB  - SPRINT.N  Eng  J  Med  2015;373(22):2103–2116-  Multicenter,  open-label,  randomized  controlled  trial  that  randomized  patients  at  high  risk  for  CVD  but  who  did  not  have  a  history  of  diabetes  or  stroke  to  an  intensive  (<120  mmHg)  vs.  standard  (<140  mmHg)  SBP  target.  Intensive  BP  control  (target  SBP  <120  mmHg)  improved  CV  outcomes  and  overall  survival  compared  to  the  standard  SBP  goal  <140  mmHg,  with  modest  increase  in  the  risk  of  some  serious  adverse  events.  Similar  benefits  were  demonstrated  in  a  CKD  subgroup  analysis  (JASN  2017:28(9):2561–2563).  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/10/12
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1189914135
ER  -