TY - CHAP M1 - Book, Section TI - Renal Toxicology A1 - Hernandez, German T. A1 - Rodriguez, Rudolph A. A2 - LaDou, Joseph A2 - Harrison, Robert J. Y1 - 2021 N1 - T2 - CURRENT Diagnosis & Treatment: Occupational & Environmental Medicine, 6e AB - In the United States, 726,331 patients were treated for end-stage renal disease (ESRD) in 2016 at an annual cost near $50 billion in Medicare expenditures. Both the number of patients and the associated costs continue to grow annually. The etiology of the kidney injury in a significant percentage of these patients is never fully elucidated, and the diagnosis of renal disease of occupational origin is rarely considered. The true incidence of chronic kidney disease (CKD) secondary to occupational and environmental exposures in the United States is unknown. However, these exposures represent potentially preventable causes of CKD. Even if occupational and environmental exposures account for only a small percentage of the causes of ESRD in the United States, the significant morbidity, mortality, and costs associated with renal replacement therapy potentially could be prevented. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180877805 ER -