TY - CHAP M1 - Book, Section TI - STRYCHNINE A1 - Nordt, Sean Patrick A2 - Olson, Kent R. A2 - Anderson, Ilene B. A2 - Benowitz, Neal L. A2 - Blanc, Paul D. A2 - Clark, Richard F. A2 - Kearney, Thomas E. A2 - Kim-Katz, Susan Y. A2 - Wu, Alan H. B. Y1 - 2018 N1 - T2 - Poisoning & Drug Overdose, 7e AB - Strychnine is an alkaloid derived from the seeds of the tree Strychnos nux-vomica. Brucine, a similar but weaker alkaloid, comes from the same seeds. Strychnine can be found in other plants (eg, Saint Ignatius bean Strychnos ignatii, Snakewood Lignum colubrinum). It is odorless and colorless, with a bitter taste. At one time, strychnine was an ingredient in a variety of over-the-counter tonics and laxatives, and was used clinically in the treatment of cardiac arrest and snake envenomation, and as an analeptic. Although strychnine is no longer found in pharmaceuticals; it is still available as a pesticide and rodenticide. It is also sometimes found as an adulterant in illicit drugs (eg, cocaine, heroin). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1179992632 ER -