TY - CHAP M1 - Book, Section TI - Cryoglobulinemia A1 - Serling-Boyd, Naomi A1 - Stone, John H. A2 - Stone, John H. Y1 - 2021 N1 - T2 - Current Diagnosis & Treatment: Rheumatology, 4e AB - Vasculitis associated with mixed cryoglobulinemia (MC) involves both small- and medium-sized vessels. The skin is the most commonly involved organ.Other frequently affected organs include the joints, peripheral nerves, and kidneys. The central nervous system, gastrointestinal tract, and lungs are involved rarely or very rarely in MC.Virtually all patients are rheumatoid factor (RF) positive.Many cases of type II cryoglobulinemia are still associated with hepatitis C virus.Lower survival rates are observed with age over 60 years, male sex, and renal involvement. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180197565 ER -