TY - CHAP M1 - Book, Section TI - Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) A1 - Seo, Philip A1 - Stone, John H. A2 - Stone, John H. Y1 - 2021 N1 - T2 - Current Diagnosis & Treatment: Rheumatology, 4e AB - Asthma, eosinophilia, and systemic vasculitis are the hallmarks of eosinophilic granulomatosis with polyangiitis (EGPA; Churg-Strauss syndrome).Classic clinical features include the following:Allergic rhinitis and nasal polyposis.Reactive airway disease.Peripheral eosinophilia (10–60% of all circulating leukocytes).Fleeting pulmonary infiltrates and occasional alveolar hemorrhage.Vasculitic neuropathy.Congestive heart failure.Approximately 50% of patients with EGPA have antineutrophil cytoplasmic antibodies (ANCAs), usually with a specificity for myeloperoxidase (MPO). SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180197443 ER -