TY - CHAP M1 - Book, Section TI - Takayasu Arteritis A1 - Unizony, Sebastian A2 - Stone, John H. Y1 - 2021 N1 - T2 - Current Diagnosis & Treatment: Rheumatology, 4e AB - Takayasu arteritis (TAK) causes granulomatous vasculitis of the aorta, main aortic branches and pulmonary arteries.Preferentially affects young women.Often presents with absent pulses, extremity claudication, hypertension, or constitutional symptoms.Erythrocyte sedimentation rate and C-reactive protein levels are usually elevated.Definitive diagnosis requires vascular imaging or biopsy.Patients respond acutely to prednisone. However, relapse upon prednisone tapering is common and glucocorticoid-sparing immunosuppressive drugs are needed for remission maintenance in most casesSubclinical progression of arterial damage despite treatment can be seen and patients should undergo periodic imaging surveillance. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180197244 ER -