TY - CHAP M1 - Book, Section TI - Hidradenitis Suppurativa A1 - Hardin, J. Matthew A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason Y1 - 2021 N1 - T2 - The Atlas of Emergency Medicine, 5e AB - Hidradenitis suppurativa (HS) most commonly affects obese, postpubertal individuals with a genetic predisposition. This unremitting disease involves intertriginous sites: axillae, inguinal folds, gluteal fold, perianal area, and inframammary folds. Lesions begin with erythematous nodules that become tender and fluctuant. The sterile abscess ruptures with a suppurative discharge, and multiple abscesses can eventuate into sinus tracts and/or fistulae. HS is primarily a noninfectious, inflammatory response to the hair follicle; however, secondary infections are common. Severe hypertrophic scar formation may be dramatic and disfiguring. In addition, chronic discharge is difficult to control and commonly malodorous. The differential diagnosis includes bacterial furunculosis, granuloma inguinale, mycetoma, cutaneous tuberculosis, and fistulas associated with inflammatory bowel disease. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1181043904 ER -