TY  - CHAP
M1  - Book, Section
TI  - Roseola Infantum (Exanthem Subitum)
A1  - Shah, Ashish
A1  - Sobolewski, Brad
A1  - Mittiga, Matthew R.
A2  - Knoop, Kevin J.
A2  - Stack, Lawrence B.
A2  - Storrow, Alan B.
A2  - Thurman, R. Jason
Y1  - 2021
N1  - 
T2  - The Atlas of Emergency Medicine, 5e
AB  - The  typical  presentation  of  roseola  infantum  involves  a  prodrome  characterized  by  a  3-  to  5-day  history  of  high  fever  often  exceeding  40°C  (104°F)  in  a  child  6  months  to  3  years  of  age.  The  child  may  be  fussy  and  have  lymphadenopathy  and  Nagayama  spots  (erythematous  papules  on  the  soft  palate  and  uvula),  but  is  often  otherwise  well  appearing.  After  the  child’s  fever  abruptly  abates,  the  typical  exanthem  appears,  characterized  by  blanching  erythematous  macules  and  papules  on  the  trunk,  neck,  proximal  extremities,  and  occasionally  the  face.  The  evanescent  rash  fades  within  2  to  4  days  but  may  only  last  several  hours.  The  causative  agent  in  90%  of  cases  is  human  herpesvirus  6  (HHV-6).  The  differential  diagnosis  includes  viruses  such  as  measles,  rubella,  parvovirus  B19,  or  infectious  mononucleosis.  Bacterial  infections  (eg,  scarlet  fever),  drug  reactions,  guttate  psoriasis,  papular  urticaria,  and  erythema  multiforme  are  also  included  in  the  differential.  
SN  - 
PB  - McGraw-Hill
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1181044330
ER  -