TY - CHAP M1 - Book, Section TI - Osteogenesis Imperfecta A1 - Singh, Manpreet A1 - Whitfield, Denise A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason Y1 - 2021 N1 - T2 - The Atlas of Emergency Medicine, 5e AB - Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder. The disease manifests on a spectrum with patients with more severe disease often suffering from fractures with minimal or no trauma. Very severe forms of disease can result in perinatal death. OI manifests most commonly as excess or atypical fractures, but other findings include short statures, hearing loss, easy bruising, and a scleral tint with the sclerae commonly appearing blue. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/10/15 UR - accessmedicine.mhmedical.com/content.aspx?aid=1181038169 ER -