TY - CHAP M1 - Book, Section TI - Medullary Sponge Kidney A1 - Dirkx, Tonja C. A1 - Woodell, Tyler B. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. Y1 - 2021 N1 - T2 - Current Medical Diagnosis & Treatment 2021 AB - This disease is a relatively common and benign disorder that is present at birth and not usually diagnosed until the fourth or fifth decade. It can be caused by autosomal dominant mutations in the MCKD1 or MCKD2 genes on chromosomes 1 and 16, respectively. Kidneys have a marked irregular enlargement of the medullary and interpapillary collecting ducts. This is associated with medullary cysts that are diffuse, giving a “Swiss cheese” appearance in these regions. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2023/01/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1177463013 ER -