TY - CHAP M1 - Book, Section TI - Patient with Bleeding Disorder - Case 3 A1 - Hoffman, Philip A2 - Stern, Scott D.C. A2 - Cifu, Adam S. A2 - Altkorn, Diane Y1 - 2020 N1 - T2 - Symptom to Diagnosis: An Evidence-Based Guide, 4e AB - PATIENT Ms. W is a 56-year-old woman who comes to the office complaining of poor appetite for several weeks and black, tarry stools with generalized weakness for 1 day.She has no prior history of bleeding, and her 3 prior obstetric deliveries were uncomplicated. Her past history is notable for cirrhosis due to chronic hepatitis C. Her medications include spironolactone and metoprolol; additionally, she has been taking ibuprofen for back pain.On examination, she is pale. Her blood pressure is 110/80 mm Hg, pulse is 112 bpm, RR is 16 breaths per minute, temperature is 37.1°C. Her conjunctivae are pale, mucous membranes moist, lungs clear, heart regular rhythm with a systolic flow murmur at the left sternal border, liver minimally enlarged with a nodular edge, spleen palpable 3 cm below the left costal margin in the anterior axillary line, and she has no edema. Digital rectal examination discloses black stool that is Hemoccult-positive.At this point, what is the leading hypothesis, what are the active alternatives, and is there a must not miss diagnosis? Given this differential diagnosis, what tests should be ordered? SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/09/11 UR - accessmedicine.mhmedical.com/content.aspx?aid=1185662795 ER -