TY - CHAP M1 - Book, Section TI - ERGOT DERIVATIVES A1 - Benowitz, Neal L. A1 - O'Connell, Charles W. A2 - Olson, Kent R. A2 - Anderson, Ilene B. A2 - Benowitz, Neal L. A2 - Blanc, Paul D. A2 - Clark, Richard F. A2 - Kearney, Thomas E. A2 - Kim-Katz, Susan Y. A2 - Wu, Alan H. B. Y1 - 2018 N1 - T2 - Poisoning & Drug Overdose, 7e AB - Ergot derivatives are used to treat migraine headache and enhance uterine contraction postpartum. Ergots are produced by the fungus Claviceps purpurea, which may grow on rye and other grains. Natural or synthetic ergot drugs include ergotamine (Cafergot, Ergomar, Gynergen, and Ergostat), dihydroergotamine (DHE45), methysergide (Sansert), methylergonovine (Methergine), and ergonovine (Ergotrate). Some ergoloid derivatives (dihydroergocornine, dihydroergocristine, and dihydroergocryptine) have been used in combination (Hydergine and Deapril-ST) for the treatment of dementia. Bromocriptine (Parlodel) and pergolide (Permax) are ergot derivatives with dopamine agonist activity that are used to treat Parkinson disease. Bromocriptine is also used to treat hyperprolactinemic states. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1174605833 ER -