TY - CHAP M1 - Book, Section TI - ANTICOAGULANTS, NEWER A1 - O'Connell, Charles W. A2 - Olson, Kent R. A2 - Anderson, Ilene B. A2 - Benowitz, Neal L. A2 - Blanc, Paul D. A2 - Clark, Richard F. A2 - Kearney, Thomas E. A2 - Kim-Katz, Susan Y. A2 - Wu, Alan H. B. Y1 - 2018 N1 - T2 - Poisoning & Drug Overdose, 7e AB - The newer target-specific oral anticoagulant medications dabigatran, rivaroxaban, apixaban, and edoxaban have become increasingly popular alternatives to the vitamin K antagonist, warfarin (see Warfarin and Superwarfarins), the former mainstay of oral anticoagulation for prevention and treatment of venous thrombus events and stroke risk reduction in atrial fibrillation. These newer drugs inhibit a single target-specific step in coagulation rather than blocking multiple vitamin K–dependent blood factors as done by warfarin. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1174604998 ER -