TY - CHAP M1 - Book, Section TI - Pancreas A1 - Lyu, Heather G. A1 - Clancy, Thomas E. A2 - Doherty, Gerard M. Y1 - 2020 N1 - T2 - Current Diagnosis & Treatment: Surgery, 15e AB - The pancreas appears in the fourth week of fetal life from the caudal part of the foregut as dorsal and ventral pancreatic buds. Both buds rotate to the right and fuse near the point of origin of the ventral pancreas. Later, as the duodenum rotates, the pancreas shifts to the left. In the adult, only the caudal portion of the head and the uncinate process are derived from the ventral pancreas. The cranial part of the head and all of the body and tail are derived from the dorsal pancreas. Most of the dorsal pancreatic duct joins with the duct of the ventral pancreas to form the main pancreatic duct (duct of Wirsung); a small part persists as the accessory duct (duct of Santorini). In 5%-10% of people, the ventral and dorsal pancreatic ducts do not fuse, a condition known as pancreatic divisum, and most regions of the pancreas drain through the duct of Santorini and the orifice of the minor papilla. In this case, only the small ventral pancreas drains with the common bile duct through the papilla of Vater. SN - PB - McGraw Hill LLC CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1171279698 ER -