TY - CHAP M1 - Book, Section TI - Dialysis A1 - Jameson, J. Larry A1 - Fauci, Anthony S. A1 - Kasper, Dennis L. A1 - Hauser, Stephen L. A1 - Longo, Dan L. A1 - Loscalzo, Joseph Y1 - 2020 N1 - T2 - Harrison's Manual of Medicine, 20e AB - The decision to initiate dialysis for the management of end-stage renal disease (ESRD) usually depends on a combination of the pt’s symptoms, comorbid conditions, and laboratory parameters. Unless a living donor is identified, transplantation is deferred by necessity, due to the scarcity of deceased donor organs (median waiting time, 3–6 years at most transplant centers). Dialytic options include hemodialysis and peritoneal dialysis (PD). Roughly 85% of U.S. pts are started on hemodialysis. All three forms of “renal replacement therapy” (RRT) require planning and preparation months to years before ESRD occurs; early referral to a nephrologist is thus critical for successful RRT. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1167067450 ER -