TY - CHAP M1 - Book, Section TI - Onchocerciasis A1 - Onyekonwu, Chinwe Laura A1 - Ozoh, Gladys Angela A1 - Ojinmah, Uche Rowland A2 - Kelly, A. Paul A2 - Taylor, Susan C. A2 - Lim, Henry W. A2 - Serrano, Ana Maria Anido Y1 - 2016 N1 - T2 - Taylor and Kelly's Dermatology for Skin of Color, 2e AB - KEY POINTSOnchocerciasis is a chronic, disabling vector-borne disease caused by infestation with the filarial nematode worm Onchocerca volvulus that not only leads to physical and psychosocial sequelae, but also causes profound socioeconomic problems.An estimated 37 million people are afflicted, especially in sub-Saharan Africa, with Nigeria accounting for about one-third of the world’s cases.Clinical presentation reflects variations in a host’s immune response to the parasite.The classic lesion is the onchocercoma, a firm, painless nodule that occurs in the subcutaneous tissue.Most of the burden of the skin disease occurs as a result of severe, intolerable pruritus.Mass treatment with ivermectin in affected communities has been highly successful in reducing the disease burden.There remains a need for sustainability of control measures to maintain the gains in management of the disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161548564 ER -