TY - CHAP M1 - Book, Section TI - Pharmacology of Vasopressors and Inotropes A1 - Shields, Sara Haney A1 - Holland, Rachel M. A2 - Tintinalli, Judith E. A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Stapczynski, J. Stephan A2 - Cline, David M. A2 - Thomas, Stephen H. Y1 - 2020 N1 - T2 - Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e AB - Vasopressors are potent pharmacologic agents that are used to increase blood pressure and mean arterial pressure by vasoconstriction, thus increasing systemic vascular resistance. They should be reserved for cases of persistent hypotension and tissue hypoperfusion after volume resuscitation has failed. Most vasopressors have proarrhythmic potential and exert effects on both the heart and vasculature. Some agents also have inotropic properties and are used to improve cardiac output, particularly in patients with left ventricular pump failure or cardiogenic shock. In patients with septic shock, the cumulative vasopressor dose to maintain blood pressure is a predictor for early death.1Table 20-12-8 provides a summary of vasopressors and inotropic agents. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166527631 ER -