TY - CHAP M1 - Book, Section TI - Lipogenic Neoplasms A1 - Mentzel, Thomas A1 - Brenn, Thomas A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCELipogenic neoplasms represent the most frequent mesenchymal neoplasms.Lipogenic neoplasms include benign neoplasms (eg, lipoma, angiolipoma), intermediate, locally aggressive, nonmetastasizing neoplasms (eg, atypical lipomatous tumor), and clearly malignant lesions (eg, pleomorphic liposarcoma).Anatomic site, depth, and size are responsible for striking differences in regard to incidence, morphology, and prognosis.The clinical presentation of lipogenic neoplasms is usually nonspecific.The majority of lipogenic neoplasms is characterized by distinct cytogenetic abnormalities that may have diagnostic and therapeutic value.Surgical excision is the treatment of choice; in cases of malignant neoplasms not amenable for complete excision radiation therapy, however, chemotherapy or target-like therapy may be used. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161337867 ER -