TY - CHAP M1 - Book, Section TI - Histiocytosis A1 - Schmieder, Astrid A1 - Goerdt, Sergij A1 - Utikal, Jochen A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCELangerhans cell histiocytosis: Translucent, rose-yellowish, crusted papules or papulovesicles, eczematous lesions, hemorrhagic papules and nodules, petechiae, noduloulcerative mucosal lesions, and nail involvementRosai-Dorfman disease: Lymphadenopathy, cutaneous nodules, and plaquesHemophagocytic lymphohistiocytosis: Various cutaneous manifestations such as erythroderma, generalized purpuric macules and papules, and morbilliform eruptionsJuvenile xanthogranuloma: Solitary as well as multiple (oligolesional) papules or nodules—early lesions show a reddish-brown color; mature lesions have a reddish-yellow appearanceBenign cephalic histiocytosis: Like juvenile xanthogranuloma; ultrastructural presence of worm-like bodiesGeneralized eruptive histiocytoma of childhood: Widespread, erythematous, essentially symmetrical papulesAdult xanthogranuloma: Oligolesional, yellow-orange papules that usually appear on the face, neck, and lower armsPapular xanthoma: Solitary yellowish papuleGeneralized eruptive histiocytoma: Multiple asymptomatic and symmetrically distributed brownish erythematous papules, particularly involving the axial regions such as the trunk, face, and proximal extremities, frequently flaresXanthoma disseminatum: Small, yellow-red to brown papules and nodules that are discrete and are disseminated with a predilection for the flexural and intertriginous areas, as well as for mucous membranesMulticentric reticulohistiocytosis: Firm, yellow-brownish papules or nodules that reach a size of several centimeters and progress slowly in size; lesions over the joints of fingers and wrists are typical; often involvement of mucosae and conjunctivaeErdheim-Chester disease: Xanthelasma and xanthoma are present in one-sixth of cases; long bone and other extracutaneous involvementNecrobiotic xanthogranuloma: Yellowish plaques and nodules that can ulcerateHereditary progressive mucinous histiocytosis: Skin-colored to red-brown papules that usually develop in the first decade on the nose, hands, forearms, and thighs that can later develop into persistent and progressive erythematous papulesProgressive nodular histiocytosis: Generalized, discrete yellow to red-brown papules and nodules measuring a few centimeters in size with prominent facial involvement SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161336567 ER -