TY - CHAP M1 - Book, Section TI - Drug Abuse A1 - Frank, Nicholas A1 - Hennings, Cara A1 - Miller, Jami L. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEDrug use is a growing problem in the United States and around the world. There are many cutaneous findings that suggest use, abuse, and addiction to drugs.Specific findings in affected patients include dental caries, madarosis, presence of scarring, tattooing, and staining in the skin.Levamisole causes a unique syndrome characterized by retiform purpura of the ears associated with neutropenia, perinuclear antineutrophil cytoplasmic antibody and anti-MPO3 antibodies.Less-specific findings of drug use include morbilliform eruptions, vasculitis, and formation of autoantibodies.Drug-use–related infections predominantly affect the skin and soft tissues. Staphylococcal species are the most common organisms, followed by streptococcal species, oral pathogens, and Candida.Other sequelae of drug use include increased risk of infections including HIV, hepatitides B and C, and syphilis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161333430 ER -