TY  - CHAP
M1  - Book, Section
TI  - Allergic Contact Dermatitis
A1  - Turrentine, Jake E.
A1  - Sheehan, Michael P.
A1  - Cruz, Jr., Ponciano D.
A2  - Kang, Sewon
A2  - Amagai, Masayuki
A2  - Bruckner, Anna L.
A2  - Enk, Alexander H.
A2  - Margolis, David J.
A2  - McMichael, Amy J.
A2  - Orringer, Jeffrey S.
Y1  - 2019
N1  - 
T2  - Fitzpatrick's Dermatology, 9e
AB  - AT-A-GLANCEAllergic  contact  dermatitis  (ACD)  is  a  cell-mediated  (type  IV),  delayed  type,  hypersensitivity  reaction  caused  by  skin  contact  with  an  environmental  allergen.Prior  sensitization  is  required  for  allergy  to  develop.The  clinical  manifestation  of  ACD  is  an  eczematous  dermatitis.  The  acute  phase  is  characterized  by  pruritus,  erythema,  edema,  and  vesicles,  usually  confined  to  the  area  of  direct  exposure.  Recurrent  contact  to  the  causative  allergen  may  lead  to  chronic  disease,  characterized  by  lichenified  erythematous  plaques  with  variable  hyperkeratosis,  fissuring,  and  pigmentary  changes  that  may  spread  beyond  the  areas  of  direct  exposure.Itch  and  swelling  are  key  components  of  the  history  and  may  be  clues  to  allergy.Patch  testing  is  the  diagnostic  test  of  choice  to  identify  causal  allergens  and  is  indicated  for  patients  with  persistent  or  recurrent  dermatitis  in  whom  ACD  is  suspected.Allergen  avoidance  is  the  mainstay  of  ACD  treatment.  Educating  patients  about  avoiding  the  allergen  and  related  substances,  and  providing  suitable  alternatives,  are  crucial  to  a  good  outcome.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1161322509
ER  -