TY - CHAP M1 - Book, Section TI - Skin A1 - Mescher, Anthony L. Y1 - 2018 N1 - T2 - Junqueira’s Basic Histology: Text and Atlas, 15e AB - The skin is the largest single organ of the body, typically accounting for 15%-20% of total body weight and, in adults, presenting 1.5-2 m2 of surface to the external environment. Also known as the integument (L. integumentum, covering) or cutaneous layer, the skin is composed of the epidermis, an epithelial layer of ectodermal origin, and the dermis, a layer of mesodermal connective tissue (Figure 18–1). At the irregular junction between the dermis and epidermis, projections called dermal papillae interdigitate with invaginating epidermal ridges to strengthen adhesion of the two layers. Epidermal derivatives include hairs, nails, and sebaceous and sweat glands. Beneath the dermis lies the subcutaneous tissue or hypodermis (Gr. hypo, under + derma, skin), a loose connective tissue layer usually containing pads of adipocytes. The subcutaneous tissue binds the skin loosely to the underlying tissues and corresponds to the superficial fascia of gross anatomy. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1160663113 ER -