TY - CHAP M1 - Book, Section TI - Hypothyroidism and Myxedema Crisis A1 - Idrose, Alzamani Mohammad A2 - Tintinalli, Judith E. A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Stapczynski, J. Stephan A2 - Cline, David M. A2 - Thomas, Stephen H. Y1 - 2020 N1 - T2 - Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e AB - Hypothyroidism is a clinical syndrome caused by insufficient thyroid hormone production, which slows cell metabolism. The prevalence of overt hypothyroidism in the general population varies between 0.3% and 3.7% in the United States, and between 0.2% and 5.3% in Europe.1-4 The prevalence of hypothyroidism increases with age (>65 years) and is higher among white individuals and women.5 The disorder is nearly 10 times more common in females than in males. On the other hand, subclinical hypothyroidism is more prevalent than overt hypothyroidism in all age groups and can be seen in 4% to 15% of women, especially the elderly.6 Myxedema coma mortality rates with current treatments are between 30% and 60%.6 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166812233 ER -