TY - CHAP M1 - Book, Section TI - Plasma Proteins & Immunoglobulins A1 - Kennelly, Peter J. A1 - Murray, Robert K. A1 - Jacob, Molly A1 - Varghese, Joe A2 - Rodwell, Victor W. A2 - Bender, David A. A2 - Botham, Kathleen M. A2 - Kennelly, Peter J. A2 - Weil, P. Anthony Y1 - 2018 N1 - T2 - Harper's Illustrated Biochemistry, 31e AB - OBJECTIVESAfter studying this chapter, you should be able to:List the major functions of blood.Describe the principal functions of serum albumin.Explain how haptoglobin protects the kidney against formation of damaging iron precipitates.Describe the roles of ferritin, transferrin, and ceruloplasmin in iron homeostasis.Describe the mechanism by which transferrin, transferrin receptors, and HFE protein regulate the synthesis of hepcidin.Explain how iron homeostasis can be perturbed by dietary deficiencies or certain disorders.Describe the general structures and functions of the five classes of immunoglobulins.Explain how up to a million different immunoglobulins can be generated utilizing fewer than 150 human genes.Describe the activation and mode of action of the complement system.Compare and contrast the adaptive and innate immune systems.Define the term lectin.Outline the key differences between polyclonal and monoclonal antibodies.Describe the salient features of autoimmune and immunodeficiency disorders. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1160193405 ER -