TY - CHAP M1 - Book, Section TI - Protein Synthesis & the Genetic Code A1 - Weil, P. Anthony A2 - Rodwell, Victor W. A2 - Bender, David A. A2 - Botham, Kathleen M. A2 - Kennelly, Peter J. A2 - Weil, P. Anthony Y1 - 2018 N1 - T2 - Harper's Illustrated Biochemistry, 31e AB - OBJECTIVESAfter studying this chapter, you should be able to:Understand that the genetic code is a three-letter nucleotide code, which is contained within the linear array of the exon DNA (composed of triplets of A, G, C, and T) of protein coding genes, and that this three-letter code is translated into mRNA (composed of triplets of A, G, C, and U) to specify the linear order of amino acid addition during protein synthesis via the process of translation.Appreciate that the universal genetic code is degenerate, unambiguous, nonoverlapping, and punctuation free.Explain that the genetic code is composed of 64 codons, 61 of which encode amino acids while 3 induce the termination of protein synthesis.Describe how the transfer RNAs (tRNAs) serve as the ultimate informational agents that decode the genetic code of messenger RNAs (mRNAs).Understand the mechanism of the energy-intensive process of protein synthesis that occurs on RNA-protein complexes termed ribosomes.Appreciate that protein synthesis, like DNA replication and transcription, is precisely controlled through the action of multiple accessory factors that are responsive to multiple extra- and intracellular regulatory signaling inputs. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/06 UR - accessmedicine.mhmedical.com/content.aspx?aid=1160191039 ER -