TY - CHAP M1 - Book, Section TI - Conversion of Amino Acids to Specialized Products A1 - Rodwell, Victor W. A2 - Rodwell, Victor W. A2 - Bender, David A. A2 - Botham, Kathleen M. A2 - Kennelly, Peter J. A2 - Weil, P. Anthony Y1 - 2018 N1 - T2 - Harper's Illustrated Biochemistry, 31e AB - OBJECTIVESAfter studying this chapter, you should be able to:Cite examples of how amino acids participate in a variety of biosynthetic processes other than protein synthesis.Outline how arginine participates in the biosynthesis of creatine, nitric oxide (NO), putrescine, spermine, and spermidine.Indicate the contribution of cysteine and of β-alanine to the structure of coenzyme A.Discuss the role played by glycine in drug catabolism and excretion.Document the role of glycine in the biosynthesis of heme, purines, creatine, and sarcosine.Identify the reaction that converts an amino acid to the neurotransmitter histamine.Document the role of S-adenosylmethionine in metabolism.Recognize the structures of tryptophan metabolites serotonin, melatonin, tryptamine, and indole 3-acetate.Describe how tyrosine gives rise to norepinephrine and epinephrine.Illustrate the key roles of peptidyl serine, threonine, and tyrosine in metabolic regulation and signal transduction pathways.Diagram the roles of glycine, arginine, and S-adenosylmethionine in the biosynthesis of creatine.Explain the role of creatine phosphate in energy homeostasis.Illustrate the formation of γ-aminobutyrate (GABA) and the rare metabolic disorders associated with defects in GABA catabolism. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1162228963 ER -