TY - CHAP M1 - Book, Section TI - LIPID METABOLISM A1 - Janson, Lee W. A1 - Tischler, Marc E. Y1 - 2018 N1 - T2 - The Big Picture: Medical Biochemistry AB - Lipids perform several essential functions, including forming biological membranes, efficient storage of energy, and as components of several important structural and functional molecules. Lipid metabolism includes both the synthesis and degradation of fatty acids and/or more complex lipid molecules. The choice between synthesis and degradation represents an important regulatory step in human biology and reflects the level of food and, therefore, energy stores available to the body. Several processes are involved in this decision of producing fatty acids/lipids or, instead, directing their precursors to energy production via carbohydrate metabolic pathways. Separate but still dependent on this process, the production of cholesterol and several lipid-derived hormones and signaling molecules is essential for multiple functions in the human body. As in most metabolic pathways, deficiencies or problems can lead to serious disease states. As seen in other chapters, understanding of the exact mechanism of these problematic metabolic steps also allows treatment of these diseases. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1152118203 ER -