TY - CHAP M1 - Book, Section TI - WOMEN AND ISCHEMIC HEART DISEASE: AN EVOLVING SAGA A1 - Shaw, Leslee J. A1 - Charney, Pamela A1 - Wenger, Nanette K. A2 - Fuster, Valentin A2 - Harrington, Robert A. A2 - Narula, Jagat A2 - Eapen, Zubin J. Y1 - 2017 N1 - T2 - Hurst's The Heart, 14e AB - SummaryThis chapter discusses ischemic heart disease (IHD) in women. IHD is the leading cause of morbidity, mortality, and disability in US women. Among all ages, women have a lower prevalence of coronary artery disease (CAD) than do men; however, once clinical manifestations of IHD develop, women have less favourable outcomes than do their male peers in the settings of stable IHD, acute coronary syndromes (ACS), and coronary revascularization. Prevention strategies in women should take into account risk factors that are unique or predominant in women, such as pregnancy complications and systemic autoimmune disorders, as well as the differential risks of traditional risk factors in men and women (see accompanying Hurst’s Central Illustration). The clinical diagnosis of angina can be challenging in women; a careful history is required to assess the likelihood of CAD and to aid decision making regarding additional testing. Noninvasive diagnostic testing can refine the management of symptomatic women. Invasive coronary angiography may be used as a frontline procedure in high-risk women or those whose symptom burden is considered unstable, or in the setting of demonstrable ischemia by stress testing. Compared with men, women with acute or stable IHD more often have nonobstructive CAD. Women with IHD are less likely than men to receive guideline-based therapy, and have worse outcomes. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1191189218 ER -