TY - CHAP M1 - Book, Section TI - ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION A1 - Patel, Manesh R. A1 - Singh, Mandeep A1 - Gersh, Bernard J. A1 - O’Neill, William A2 - Fuster, Valentin A2 - Harrington, Robert A. A2 - Narula, Jagat A2 - Eapen, Zubin J. Y1 - 2017 N1 - T2 - Hurst's The Heart, 14e AB - Ischemic heart disease is the leading cause of morbidity and mortality in Western society and is a worldwide epidemic. In 2008, it was estimated that, worldwide, ischemic heart disease was responsible for 12.7% of all deaths (7.25 million total). Low-income countries now account for 80% of all deaths; mortality is falling in high-income countries.1 Approximately 1,100,000 Americans suffer from an acute coronary syndrome (ACS) per year, nearly one-third of which are caused by an acute ST-segment elevation myocardial infarction (STEMI).2 The incidence of acute myocardial infarction (AMI) has declined over the past two decades from 244 per 100,000 population in 1975 to 162 per 100,000 population in 2006.3 The in-hospital mortality also has declined from 18% in 1975 to 10% in 2006.4 Despite these improvements, AMI continues to be a major public health problem, and it has been estimated that the number of years of life lost because of an AMI is 17.1 years, and the cost to American society (both direct and indirect) is $165.4 billion per year.2 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161730249 ER -