TY - CHAP M1 - Book, Section TI - Clinical Use of Antimicrobial Agents A1 - Lampiris, Harry W. A1 - Maddix, Daniel S. A2 - Katzung, Bertram G. Y1 - 2017 N1 - T2 - Basic & Clinical Pharmacology, 14e AB - CASE STUDYA 65-year-old man undergoes cystoscopy because of the presence of microscopic hematuria in order to rule out urologic malignancy. The patient has mild dysuria and pyuria and empirically receives oral therapy with ciprofloxacin for presumed urinary tract infection prior to the procedure and tolerates the procedure well. Approximately 48 hours after the procedure, the patient presents to the emergency department with confusion, dysuria and chills. Physical exam reveals a blood pressure of 90/50, pulse of 120, temperature of 38.5° C and respiratory rate of 24. The patient is disoriented but the physical exam is otherwise unremarkable. Laboratory test shows WBC 24,000/mm3 and elevated serum lactate; urinalysis shows 300 WBC per high power field and 4+ bacteria. What possible organisms are likely to be responsible for the patient’s symptoms? At this point, what antibiotic(s) would you choose for initial therapy of this potentially life-threatening infection? SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1148441090 ER -