TY  - CHAP
M1  - Book, Section
TI  - Multifactorial Inheritance and Gene × Environment Interactions
A1  - Schaefer, G. Bradley
A1  - Thompson, Jr., James N.
Y1  - 2017
N1  - 
T2  - Medical Genetics: An Integrated Approach
AB  - The  study  of  human  inheritance  often  tends  to  focus  on  relatively  simple  traits.  But  as  we  explored  in  Chapter  2  and  elsewhere,  there  is  a  broad  avenue  of  molecular  and  developmental  events  that  connect  the  DNA  with  a  phenotype.  When  the  work  of  Gregor  Mendel  was  "rediscovered"  in  1900,  various  researchers  attempted  to  repeat  and  confirm  his  observations  using  a  variety  of  plants  and  animals,  including  humans.  Some  studies  supported  the  Mendelian  genetic  models.  But  many  other  cases  were  unsuccessful  either  because  the  organisms  they  chose  had  unusual  genetic  characteristics,  like  honeybee  drones  that  are  haploid,  or  because  the  traits  they  looked  at  did  not  have  the  simple  phenotypic  basis  that  we  see  in  those  studied  by  Mendel.  Some  people  attribute  these  latter  studies  to  bad  luck  in  choosing  an  experimental  system.  But  in  fact  they  were  setting  the  stage  to  explore  a  parallel,  and  very  important,  dimension  of  genetic  complexity.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1147722966
ER  -