TY - CHAP M1 - Book, Section TI - The Organization of Development A1 - Schaefer, G. Bradley A1 - Thompson, Jr., James N. Y1 - 2017 N1 - T2 - Medical Genetics: An Integrated Approach AB - A conclusion one could draw from the first two chapters is that the role of genes in determining phenotypes is complex and dynamic. That is true. It is an important insight that should be kept in mind when evaluating a genetic question. But, by the same token, complexity does not necessarily mean that rules and order are weak. In this chapter we will explore some of these rules, specifically the question of how gene regulation activates a particular gene in the appropriate developmental context and how molecular signals carry out large-scale patterning to organize the structure of the body in early development. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1147722129 ER -