TY - CHAP M1 - Book, Section TI - Iron Homeostasis: Deficiency and Overload A1 - Bunn, H. Franklin A1 - Heeney, Matthew M. A2 - Aster, Jon C. A2 - Bunn, H. Franklin Y1 - 2016 N1 - T2 - Pathophysiology of Blood Disorders, 2e AB - LEARNING OBJECTIVESAfter studying this chapter, you should be able to:Construct a flow diagram depicting iron homeostasis: absorption from the gut, transport in the plasma, incorporation into erythroid precursors, release from senescent red cells, and return to the plasma.Explain the important role of hepcidin in regulating iron absorption from the gut and iron release from macrophages.Name and prioritize the causes of iron deficiency.Describe the key clinical and laboratory features of iron deficiency.Identify the causes of iron overload and its clinical manifestations. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1175061476 ER -