TY - CHAP M1 - Book, Section TI - Colorectal Cancer A1 - Morris, Van A1 - Subbiah, Ishwaria M. A1 - Kopetz, Scott A1 - Eng, Cathy A2 - Kantarjian, Hagop M. A2 - Wolff, Robert A. Y1 - 2016 N1 - T2 - The MD Anderson Manual of Medical Oncology, 3e AB - Colorectal cancer is a major cause of cancer-related mortality in the world. It is currently the third-most-common cancer in incidence in the United States and accounts for about 8.5% of all cancer-related mortality (nearly 136,000 new cases and 50,000 deaths each year) (1). This chapter reviews our current understanding of colorectal cancer, describes the known genetic mutations and risk factors, and outlines emerging screening, prevention, and therapeutic strategies, with particular emphasis on the approach taken at MD Anderson Cancer Center (MDACC). SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1126742634 ER -