TY - CHAP M1 - Book, Section TI - Barrett Esophagus A1 - Jajoo, Kunal A1 - Saltzman, John R. A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert Y1 - 2016 N1 - T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e AB - ESSENTIALS OF DIAGNOSISReplacement of normal squamous epithelium of the distal esophagus with specialized intestinal metaplasia.Endoscopy and biopsy are essential for an accurate diagnosis.Presence of high-grade dysplasia should be confirmed by two expert gastrointestinal pathologists.Risk factors for progression to adenocarcinoma include a large hiatal hernia, long segment of Barrett esophagus, and mucosal abnormalities (nodules, ulcerations, or strictures). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1119986649 ER -