TY  - CHAP
M1  - Book, Section
TI  - Hepatic Complications of Pregnancy
A1  - Hashemi, Nikroo
A1  - Ukomado, Chinweike
A2  - Greenberger, Norton J.
A2  - Blumberg, Richard S.
A2  - Burakoff, Robert
Y1  - 2016
N1  - 
T2  - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e
AB  - ESSENTIAL  CONCEPTSMost  liver  biochemical  tests  are  unchanged  during  pregnancy.Exceptions  are  serum  albumin,  total  protein,  and  bilirubin  (decreased)  and  alkaline  phosphatase  and  cholesterol  (increased).Several  conditions  unique  to  pregnancy  may  lead  to  hepatic  impairment:Hyperemesis  gravidarum  (HG),  often  in  the  first  trimester,  invariably  before  the  20th  week  of  pregnancy.Intrahepatic  cholestasis  of  pregnancy  (ICP),  often  in  the  second  or  third  trimester  (pruritus  and  mild  liver  tests  abnormalities).Acute  fatty  liver  disease  of  pregnancy  (AFLP)  in  the  third  trimester  (nausea  and  vomiting,  abdominal  pain,  jaundice,  oliguria,  hypertransaminasemia,  hyperbilirubinemia,  coagulopathy,  thrombocytopenia,  renal  failure,  and  hypoglycemia).Preeclampsia  (classic  triad  of  hypertension,  proteinuria,  and  edema)  and  eclampsia  (preeclamptic  triad  plus  seizures  and  coma)  in  the  second  or  third  trimester.HELLP  syndrome  (hemolysis,  elevated  liver  enzymes,  and  low  platelets),  between  the  start  of  the  third  trimester  and  the  immediate  postpartum  period,  often  manifesting  as  weight  gain,  right  upper  quadrant  pain,  edema,  and  hypertension.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/17
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1119986083
ER  -