TY  - CHAP
M1  - Book, Section
TI  - Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections
A1  - Phillips, Margaret A.
A1  - Stanley, Samuel L.
A2  - Brunton, Laurence L.
A2  - Chabner, Bruce A.
A2  - Knollmann, Björn C.
Y1  - 2015
N1  - 
T2  - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e
AB  - Humans  host  a  wide  variety  of  protozoal  parasites  that  can  be  transmitted  by  insect  vectors,  directly  from  other  mammalian  reservoirs  or  from  one  person  to  another.  Because  protozoa  multiply  rapidly  in  their  hosts  and  effective  vaccines  are  unavailable,  chemotherapy  has  been  the  only  practical  way  to  both  treat  infected  individuals  and  reduce  transmission.  The  immune  system  plays  a  crucial  role  in  protecting  against  the  pathological  consequences  of  protozoal  infections.  Thus,  opportunistic  infections  with  protozoa  are  prominent  in  infants,  individuals  with  cancer,  transplant  recipients,  those  receiving  immunosuppressive  drugs  or  extensive  antibiotic  therapy,  and  persons  with  advanced  human  immunodeficiency  virus  (HIV)  infection.  Treatment  of  protozoal  infections  in  immunocompromised  individuals  is  especially  difficult,  and  the  outcome  is  often  unsatisfactory.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2023/09/26
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1127870390
ER  -