TY  - CHAP
M1  - Book, Section
TI  - Pulmonary Langerhans’ Cell Histiocytosis
A1  - Harari, Sergio
A1  - Torre, Olga
A1  - King, Talmadge E.
A1  - Moss, Joel
A2  - Grippi, Michael A.
A2  - Elias, Jack A.
A2  - Fishman, Jay A.
A2  - Kotloff, Robert M.
A2  - Pack, Allan I.
A2  - Senior, Robert M.
A2  - Siegel, Mark D.
PY  - 2015
T2  - Fishman's Pulmonary Diseases and Disorders, 5e
AB  - Pulmonary  Langerhans’  cell  histiocytosis  is  part  of  a  large  spectrum  of  disorders  characterized  by  abnormal  organ  infiltration  by  Langerhans’  cells,  which  are  highly  differentiated  cells  in  the  monocyte-macrophage  line  that  are  also  found  in  the  dermis  of  the  skin,  reticuloendothelial  system,  pleura,  and  lung.  Clinically,  these  disorders  vary  greatly,  ranging  from  mild,  single-organ  disease  to  acute,  disseminated  life-threatening  presentations.  Depending  on  the  sites  involved  and  severity,  the  entity  now  referred  to  as  Langerhans’  cell  histiocytosis  has  been  previously  defined  as  eosinophilic  granuloma,  Hand–Schüller–Christian  disease,  and  Letterer–Siwe  disease.  A  more  recent  and  simplified  system  of  classification  includes  Langerhans’  cell  histiocytosis  with  single-organ  involvement  or  with  multisystem  involvement.1  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1122361335
ER  -