TY - CHAP M1 - Book, Section TI - Bullous Disease of the Lung A1 - Martinez, Fernando J. A2 - Grippi, Michael A. A2 - Elias, Jack A. A2 - Fishman, Jay A. A2 - Kotloff, Robert M. A2 - Pack, Allan I. A2 - Senior, Robert M. A2 - Siegel, Mark D. PY - 2015 T2 - Fishman's Pulmonary Diseases and Disorders, 5e AB - A bulla is an air-containing space within the lung parenchyma that arises from destruction, dilatation, and confluence of airspaces distal to terminal bronchioles and is larger than 1 cm in diameter (Fig. 52-1).1 Its walls are composed of attenuated and compressed parenchyma. Bullae occur in various clinical contexts: (1) with emphysema (“bullous emphysema”); (2) with pulmonary fibrosis, as in the late stages of sarcoidosis or complicated pneumoconiosis; (3) in so-called “vanishing lung,” in which the parenchyma is rapidly replaced by multiple bullae; and (4) in lungs that are otherwise normal (“bullous lung disease”) and, therefore, likely secondary to a mechanism different from that of bullae occurring in conjunction with emphysema (Table 52-1).2,3 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1122360256 ER -