TY  - CHAP
M1  - Book, Section
TI  - Acid–Base Balance
A1  - Goldfarb, Stanley
A1  - Sharma, Kumar
A2  - Grippi, Michael A.
A2  - Elias, Jack A.
A2  - Fishman, Jay A.
A2  - Kotloff, Robert M.
A2  - Pack, Allan I.
A2  - Senior, Robert M.
A2  - Siegel, Mark D.
PY  - 2015
T2  - Fishman's Pulmonary Diseases and Disorders, 5e
AB  - Regulation  of  [H+]  is  of  crucial  importance  for  maintenance  of  normal  cellular  functions.  The  normal  [H+]  is  maintained  at  about  40  nEq/L.  When  there  is  even  a  small  change  in  the  [H+],  intracellular  proteins  gain  or  lose  H+  ions  resulting  in  alterations  in  charge  distribution  which  may  affect  molecular  structure  and  protein  function.  The  hydrogen  ion  concentration  in  bodily  fluids  is  largely  regulated  by  the  ratio  of  the  concentrations  of  carbon  dioxide  and  bicarbonate.  This  is  predicated  upon  the  relationship  demonstrated  in  the  Henderson–Hasselbalch  equation:  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1122355529
ER  -