TY - CHAP M1 - Book, Section TI - Acute Leukemias A1 - Aster, Jon C. A1 - DeAngelo, Daniel J. A2 - Bunn, H. Franklin A2 - Aster, Jon C. PY - 2011 T2 - Pathophysiology of Blood Disorders AB - LEARNING OBJECTIVESAfter studying this chapter you should understand:The pathogenic role of mutations in genes encoding transcription factors and signaling molecules in acute leukemia.The diagnostic and prognostic role of immunophenotyping, cytogenetics, and molecular genetics in acute leukemia.The general approach to treatment of patients with acute leukemia and the associated short-term complications.The unique role of "differentiating" agents in the treatment of acute promyelocytic leukemia. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/11/03 UR - accessmedicine.mhmedical.com/content.aspx?aid=1104131741 ER -