TY - CHAP M1 - Book, Section TI - Megaloblastic Anemias A1 - Bunn, H. Franklin A1 - Heeney, Matthew A2 - Bunn, H. Franklin A2 - Aster, Jon C. PY - 2011 T2 - Pathophysiology of Blood Disorders AB - LEARNING OBJECTIVESAfter studying this chapter you should be able to:Draw a simple scheme outlining the key biochemical reactions involving cobalamin (vitamin B12) and folate.Understand how cobalamin and folate are absorbed from the gut and transported in plasma.Explain the mechanisms that cause megaloblastic morphology in the bone marrow and blood and describe these features.List the causes of cobalamin deficiency.List the causes of folate deficiency. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1104130987 ER -