TY - CHAP M1 - Book, Section TI - Iron Homeostasis: Deficiency and Overload A1 - Bunn, H. Franklin A1 - Heeney, Matthew M. A2 - Bunn, H. Franklin A2 - Aster, Jon C. PY - 2011 T2 - Pathophysiology of Blood Disorders AB - LEARNING OBJECTIVESAfter studying this chapter you should be able to:Construct a flow diagram depicting iron homeostasis: absorption from the gut, transport in the plasma, incorporation into erythroid precursors, release from senescent red cells, and return to the plasma.Explain the important role of hepcidin in iron absorption from the gut and release of iron from macrophages.Name and prioritize the causes of iron deficiency.Describe the key laboratory features of iron deficiency.Identify the causes of iron overload and its clinical manifestations. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1104130921 ER -