TY - CHAP M1 - Book, Section TI - Epidermolysis Bullosa A1 - Daniel, Benjamin S. A1 - Murrell, Dedee F. A2 - Murray, Michael F. A2 - Babyatsky, Mark W. A2 - Giovanni, Monica A. A2 - Alkuraya, Fowzan S. A2 - Stewart, Douglas R. PY - 2014 T2 - Clinical Genomics: Practical Applications in Adult Patient Care AB - Disease summary:Inherited epidermolysis bullosa (EB) is a heterogenous group of genodermatoses characterized by blisters and erosions after minimal trauma. There are four main types of EB, namely epidermolysis bullosa simplex (EBS), junctional epidermolysis bullosa (JEB), dystrophic epidermolysis bullosa (DEB), and mixed Kindler syndrome. Diagnosis is made by a combination of electron microscopy (EM) and immunofluorescence findings. Management consists of avoiding trauma and preventing complications. In lethal cases, supportive measures are instituted as well as providing emotional and financial support for families or carers.Hereditary basis:Autosomal recessive and autosomal dominantDifferential diagnosis:Bullous pemphigoid, pemphigus vulgaris, linear IgA disease, arthropod bites, bullous lupus erythematosus, epidermolysis bullosa acquisita SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1102704238 ER -