TY - CHAP M1 - Book, Section TI - Renal Cell Carcinoma A1 - Newlin, Anna A1 - Hulick, Peter A2 - Murray, Michael F. A2 - Babyatsky, Mark W. A2 - Giovanni, Monica A. A2 - Alkuraya, Fowzan S. A2 - Stewart, Douglas R. PY - 2014 T2 - Clinical Genomics: Practical Applications in Adult Patient Care AB - Disease summary:Approximately 50,000 new cases of renal cell carcinoma (RCC) are diagnosed each year.RCCs are adenocarcinomas derived from renal tubular epithelium. Renal carinoma is comprised of several different types of cancer, each with a different histologic type, with a different clinical course, responding differently to therapy, and caused by different genes.Histologically, there are five subtypes: Conventional (clear cell) (70%-80%)Chromophile (papillary) (10%-15%). Papillary is further classified into type 1 (5%) and type 2 (10% of cases) based on further genetic alterations, histologic, and genetic criteriaChromophobe (3%-5%)Collecting duct (1%)Unclassified (1%) SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1102700862 ER -