TY  - CHAP
M1  - Book, Section
TI  - Chapter 180. Lupus: Systemic and Cutaneous
A1  - Usatine, Richard P.
A1  - Smith, Mindy A.
A1  - Chumley, Heidi S.
A1  - Mayeaux, E.J.
PY  - 2013
T2  - The Color Atlas of Family Medicine, 2e
AB  - A  39-year-old  black  woman  presented  to  the  clinic  with  2  months  of  swelling  of  her  upper  lip  and  cheeks  with  new  dark  spots  on  her  face  (Figure  180-1).  An  antinuclear  antibody  (ANA)  was  positive  at  a  1:80  dilution.  A  homogeneous  nuclear  pattern  was  present  as  commonly  seen  in  systemic  lupus  erythematosus  (SLE)  and  drug-induced  lupus.  The  punch  biopsy  of  a  facial  lesion  was  consistent  with  chronic  cutaneous  lupus  erythematosus  (discoid  lupus).  The  remainder  of  her  laboratory  tests  were  normal.  The  patient's  facial  lesions  did  not  respond  to  topical  steroids  and  hence  she  was  started  on  a  short  course  of  systemic  steroids.  The  improvement  was  seen  3  weeks  later  (Figure  180-2).  Hyperpigmentation  remained  but  erythema,  swelling,  and  pruritus  were  gone.  The  patient  did  not  meet  criteria  for  SLE  and  it  is  possible  to  have  discoid  lupus  with  a  positive  ANA.  Treatment  with  hydroxychloroquine  was  discussed.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=57682396
ER  -