TY - CHAP M1 - Book, Section TI - Chapter 74. Skin Findings in Pregnancy A1 - Usatine, Richard P. A1 - Smith, Mindy A. A1 - Chumley, Heidi S. A1 - Mayeaux, E.J. PY - 2013 T2 - The Color Atlas of Family Medicine, 2e AB - A 32-year-old G3P2 woman presents with persistent itching in her 31st week of pregnancy. The itching is constant and worse at night. Her pregnancy had been uncomplicated and she has no past history of medical problems. Many excoriations are noted and there are no blisters (Figure 74-1). She has no jaundice or scleral icterus. Her transaminases were greater than 300 and her total bilirubin was elevated at 2.1. Her bile salts were elevated and her hepatitis panel was negative. The ultrasound showed gallstones but no obstruction was seen. A diagnosis of “intrahepatic cholestasis of pregnancy” was made and the patient was treated with oral ursodiol (a bile salt binding agent) and topical 1% hydrocortisone cream. The bile salts and transaminases were decreased and the patient's pruritus improved but did not resolve until after delivery.1 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=57674926 ER -