TY - CHAP M1 - Book, Section TI - Chapter 44. Gout A1 - Burns, Christopher A1 - Wortmann, Robert L. A2 - Imboden, John B. A2 - Hellmann, David B. A2 - Stone, John H. PY - 2013 T2 - CURRENT Diagnosis & Treatment: Rheumatology, 3e AB - Caused by deposition of uric acid crystals and usually associated with hyperuricemia.Usually begins as an intermittent, acute monoarthritis, especially of the first metatarsophalangeal joint.Over time, attacks become more frequent, less intense, and involve more joints.Diagnosed by demonstrating uric acid crystals in joint fluid.Extra-articular manifestations include tophi and renal stones.Arthritis responds to nonsteroidal anti-inflammatory drugs or colchicine. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=57273972 ER -